PLGA Microspheres of hGH of Preserved Native State Prepared Using a Self-Regulated Process

• Main Authors: Jebun Nessa Diana (Author), Ying Tao (Author), Qiran Du (Author), Meng Wang (Author), Chinta Uday Kumar (Author), Fei Wu (Author), Tuo Jin (Author)
• פורמט: ספר
• יצא לאור: MDPI AG, 2020-07-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

The challenges of formulating recombinant human growth hormone (rhGH) into sustained-release polymeric microspheres include two mutual causal factors, protein denaturing by the formulation process and severe initial burst release related with relative high dose. The stabilizers to protect the protei...