Influence of the leukoreduction moment of blood components on the clinical outcomes of transfused patients in the emergency department
ABSTRACT Objectives: to investigate the influence of the leukoreduction moment (preor post-storage) of blood components on the clinical outcomes of patients transfused in the emergency department. Methods: retrospective cohort study of patients aged 18 years or older who received preor post-storage...
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| Main Authors: | , , , |
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| Format: | Book |
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Associação Brasileira de Enfermagem,
2024-08-01T00:00:00Z.
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| Summary: | ABSTRACT Objectives: to investigate the influence of the leukoreduction moment (preor post-storage) of blood components on the clinical outcomes of patients transfused in the emergency department. Methods: retrospective cohort study of patients aged 18 years or older who received preor post-storage leukoreduced red blood cell or platelet concentrate in the emergency department and remained in the institution for more than 24 hours. A generalized mixed-effects model was applied in the analyses. Results: in a sample of 373 patients (63.27% male, mean age 54.83) and 643 transfusions (69.98% red blood cell), it was identified that the leukoreduction moment influenced the length of hospital stay (p<0.009), but was not dependent on the transfused blood component (p=0.124). The leukoreduction moment had no effect (p>0.050) on transfusion reactions, healthcare-associated infections, or mortality. Conclusions: patients who received pre-storage leukoreduced blood components in the emergency department had a shorter length of hospital stay. |
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| Item Description: | 1984-0446 10.1590/0034-7167-2023-0293 |