A gene-protein assay for human epidermal growth factor receptor 2 (HER2): brightfield tricolor visualization of HER2 protein, the <it>HER2</it> gene, and chromosome 17 centromere (CEN17) in formalin-fixed, paraffin-embedded breast cancer tissue sections

• Main Authors: Nitta Hiroaki (Author), Kelly Brian D (Author), Padilla Mary (Author), Wick Nikolaus (Author), Brunhoeber Patrick (Author), Bai Isaac (Author), Singh Shalini (Author), Ranger-Moore Jim (Author), Bieniarz Chris (Author), Tsuda Hitoshi (Author), Grogan Thomas M (Author)
• Format: Book
• Published: BMC, 2012-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>The eligibility of breast cancer patients for human epidermal growth factor receptor 2 (HER2)-directed therapies is determined by the <it>HER2</it> gene amplification and/or HER2 protein overexpression status of the breas...