Therapeutic Treatment of Arthritic Mice with 15-Deoxy Δ12,14-Prostaglandin J2 (15d-PGJ2) Ameliorates Disease through the Suppression of Th17 Cells and the Induction of CD4+CD25−FOXP3+ Cells

• Κύριοι συγγραφείς: Vanessa Carregaro (Συγγραφέας), Marcelo H. Napimoga (Συγγραφέας), Raphael S. Peres (Συγγραφέας), Luciana Benevides (Συγγραφέας), Laís Amorim Sacramento (Συγγραφέας), Larissa G. Pinto (Συγγραφέας), Renata Grespan (Συγγραφέας), Thiago M. Cunha (Συγγραφέας), João Santana da Silva (Συγγραφέας), Fernando Q. Cunha (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: Hindawi Limited, 2016-01-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

The prostaglandin, 15-deoxy Δ12,14-prostaglandin J2 (15d-PGJ2), is a lipid mediator that plays an important role in the control of chronic inflammatory disease. However, the role of prostanoid in rheumatoid arthritis (RA) is not well determined. We demonstrated the therapeutic effect of 15d-PGJ2 in...