Evaluation the level of vitamin D and its relationship with clinical symptoms in patients with COVID-19 referred to the medical center in Bam city

• Main Authors: Mortazavi, Seyed Mojtaba (Author), Khoshnood, Saeed (Author), Faraji, Reza (Author), Baravati, Rezvan Bagheri (Author), Khalili, Hakime (Author), Radfar, Ali (Author), Jalali, Elham (Author), Nezam Nia, Maria (Author), Akrami, Sousan (Author), Shirani, Maryam (Author)
• Format: Book
• Published: German Medical Science GMS Publishing House, 2024-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Summary

Background: Vitamin D is a steroid hormone that protects against viral infections by influencing innate and adaptive immune responses. The effectiveness of vitamin D3 supplementation in COVID-19 is unknown. The study's goal was to elucidate the relationship between blood vitamin D levels and COVID-19 clinical outcomes by examining the effect of a single high dose of vitamin D3 on the length of hospital stay in patients. Methods: The descriptive, retrospective study was performed from March to May 2021 at a referral center for patients with COVID-19, in Bam, Iran. A checklist consisting of demographic variables was used to gather data, and laboratory assessments of serum 25(OH) D were evaluated and documented. The connection between serum vitamin D and patient clinical outcomes was investigated after patients were given a single oral dose of 200,000 IU of vitamin D3. Results: 71 COVID-19 patients were treated. Radiological results did not change substantially amongst individuals with various levels of 25(OH)D. After a single dosage of vitamin D3, mean blood levels of xyvitamin D increased considerably and the need for intubation and SpO decreased, and as did the respiratory rate in patients requiring hospitalization due to COVID-19. Conclusion: A single administration of 200,000 IU of vitamin D3 significantly reduced the severity of COVID-19.

Item Description

2196-5226
10.3205/dgkh000512