Bistable Bacterial Growth Dynamics in the Presence of Antimicrobial Agents

• Main Authors: Nelly Frenkel (Author), Ron Saar Dover (Author), Eve Titon (Author), Yechiel Shai (Author), Vered Rom-Kedar (Author)
• Format: Book
• Published: MDPI AG, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The outcome of an antibiotic treatment on the growth capacity of bacteria is largely dependent on the initial population size (Inoculum Effect). We characterized and built a model of this effect in <i>E. coli</i> cultures using a large variety of antimicrobials, including conventional an...