Stability of Methylphenidate under Various pH Conditions in the Presence or Absence of Gut Microbiota

• 主要な著者: Julia Aresti-Sanz (著者), Markus Schwalbe (著者), Rob Rodrigues Pereira (著者), Hjalmar Permentier (著者), Sahar El Aidy (著者)
• フォーマット: 図書
• 出版事項: MDPI AG, 2021-07-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Methylphenidate is one of the most widely used oral treatments for attention-deficit/hyperactivity disorder (ADHD). The drug is mainly absorbed in the small intestine and has low bioavailability. Accordingly, a high interindividual variability in terms of response to the treatment is known among ADH...