Blockage of S100A8/A9 ameliorates septic nephropathy in mice

• Main Authors: Wei Shi (Author), Tian-Tian Wan (Author), Hui-Hua Li (Author), Shu-Bin Guo (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Septic acute kidney injury (AKI) is the commonest cause of complication of sepsis in intensive care units, but its pathophysiology remains unclear. Calprotectin (S100A8/A9), which is a damage-associated molecular patterns (DAMPs) molecule, exerts a critical role in modulating leukocyte recruitment a...