Immunization of mice with recombinant mosquito salivary protein D7 enhances mortality from subsequent West Nile virus infection via mosquito bite.

• Autori principali: Krystle L Reagan (Autore), Carlos Machain-Williams (Autore), Tian Wang (Autore), Carol D Blair (Autore)
• Natura: Libro
• Pubblicazione: Public Library of Science (PLoS), 2012-01-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Mosquito salivary proteins (MSPs) modulate the host immune response, leading to enhancement of arboviral infections. Identification of proteins in saliva responsible for immunomodulation and counteracting their effects on host immune response is a potential strategy to protect against arboviral dise...