ROS-1 re-arrangements and c-MET amplifications in adenocarcinoma lung: A tertiary care center study from North India

• Main Authors: Saumya Shukla (Author), Rahul K Pandey (Author), Surya Kant (Author), Rajiv Garg (Author), Nuzhat Husain (Author)
• Format: Book
• Published: Wolters Kluwer Medknow Publications, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: C-ros oncogene 1, receptor tyrosine kinase (ROS 1) proto-oncogene 1, receptor tyrosine kinase (ROS-1) fusions are potent oncogenic drivers and these re-arrangements promote signal transduction programs leading to uninhibited cell survival and proliferation identified in 1-2% of cases of...