Targeting Multiple Mitochondrial Processes by a Metabolic Modulator Prevents Sarcopenia and Cognitive Decline in SAMP8 Mice

• Main Authors: Dario Brunetti (Author), Emanuela Bottani (Author), Agnese Segala (Author), Silvia Marchet (Author), Fabio Rossi (Author), Fiorenza Orlando (Author), Marco Malavolta (Author), Michele O. Carruba (Author), Costanza Lamperti (Author), Mauro Provinciali (Author), Enzo Nisoli (Author), Alessandra Valerio (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The age-dependent declines of skeletal muscle and cognitive functions often coexist in elderly subjects. The underlying pathophysiological mechanisms share common features of mitochondrial dysfunction, which plays a central role in the development of overt sarcopenia and/or dementia. Dietary supplem...