Dual Chemotherapeutic Loading in Oxalate Transferrin-Conjugated Polymersomes Incorporated into Chitosan Hydrogels for Site-Specific Targeting of Melanoma Cells

• Main Authors: Mariana de C. Aranha (Author), Luciana M. R. Alencar (Author), Eliana B. Souto (Author), Daniel T. Kamei (Author), André M. Lopes (Author)
• Format: Book
• Published: MDPI AG, 2024-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In this work, we developed a smart drug delivery system composed of poly (ethylene glycol)-<i>block</i>-poly (ε-caprolactone) (PEG-PCL)-based polymersomes (Ps) loaded with doxorubicin (DOX) and vemurafenib (VEM). To enhance targeted delivery to malignant melanoma cells, these drug-loaded...