Celastrol ameliorates liver metabolic damage caused by a high-fat diet through Sirt1

• Main Authors: Yinliang Zhang (Author), Chao Geng (Author), Xiaoyan Liu (Author), Meixia Li (Author), Mingyue Gao (Author), Xiaojun Liu (Author), Fude Fang (Author), Yongsheng Chang (Author)
• Format: Book
• Published: Elsevier, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Celastrol was recently identified as a potential novel treatment for obesity. However, the effect of Celastrol on nonalcoholic fatty liver disease (NAFLD) remains elusive. The aim of this study is to evaluate the role of Celastrol in NAFLD. Methods: Functional studies were performed using...