Effects of Folinic Acid Administration on Lower Limb Ischemia/Reperfusion Injury in Rats

• Main Authors: Iñigo Cearra (Author), Borja Herrero de la Parte (Author), Inmaculada Ruiz Montesinos (Author), Ana Alonso-Varona (Author), Diana Isabel Moreno-Franco (Author), Ignacio García-Alonso (Author)
• Format: Book
• Published: MDPI AG, 2021-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Surgery under ischemic conditions, lasting up to 3 h, is routinely performed in orthopedic surgery, causing undesirable injury due to ischemia-reperfusion syndrome, with short and medium-term functional repercussions. To date, there is no established prophylactic treatment. In this work we evaluated...