Atypical teratoid/rhabdoid tumour with CDK6 amplification in a child: a case report and literature review

• Main Authors: Zhibin Li (Author), Yubo Wang (Author), Yuanhao Liu (Author), Yining Jiang (Author), Xuefei Han (Author), Liyan Zhao (Author), Yunqian Li (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Atypical teratoid/rhabdoid tumours (AT/RTs) are rare central nervous system neoplasms that frequently occur in infants and children and have a very poor prognosis. In recent years, molecular analysis of AT/RTs has shown that biallelic inactivation of SMARCB1 (INI1, SNF5, BAF47) or SMARCA4 (BRG1) fre...