NRF2 Mediates Therapeutic Resistance to Chemoradiation in Colorectal Cancer through a Metabolic Switch
Radiation resistance is a significant clinical problem in rectal cancer treatment, the mechanisms of which are poorly understood. NRF2 signalling is known to contribute to chemo/radioresistance in some cancers, but its role in therapeutic resistance in colorectal cancer (CRC) is unexplored. Using si...
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Main Authors: | Séan M. O'Cathail (Author), Chieh-Hsi Wu (Author), Rachael Thomas (Author), Maria A. Hawkins (Author), Tim S. Maughan (Author), Annabelle Lewis (Author) |
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Format: | Book |
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MDPI AG,
2021-08-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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