Cover Image

Natural Compound Library Screening Identifies Oroxin A for the Treatment of Myocardial Ischemia/Reperfusion Injury

Myocardial ischemia/reperfusion injury (MI/RI) is a serious pathophysiological process relating to cardiovascular disease. Oroxin A (OA) is a natural flavonoid glycoside with various biological activities. However, its effect on the pathophysiological process of MI/RI has not yet been reported. The...

Full description

Saved in:

Bibliographic Details
Main Authors:	Xingdong Cheng (Author), Tingting Huang (Author), Chunhui Wang (Author), Shuang Hao (Author), Liliang Shu (Author), Shixiong Wang (Author), Gao Cheng (Author), Qiaoyun Zhang (Author), Jian Huang (Author), Chen Chen (Author)
Format:	Book
Published:	Frontiers Media S.A., 2022-05-01T00:00:00Z.
Subjects:	article
Online Access:	Connect to this object online.
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Dexamethasone Alleviates Myocardial Injury in a Rat Model of Acute Myocardial Infarction Supported by Venoarterial Extracorporeal Membrane Oxygenation
by: Xingdong Cheng, et al.
Published: (2022)

Oroxin B Attenuates Ovariectomy-Induced Bone Loss by Suppressing Osteoclast Formation and Activity
by: Huang JM, et al.
Published: (2021)

The Cardioprotective Effect of Protocatechuic Acid on Myocardial Ischemia/Reperfusion Injury
by: Xi-Lan Tang, et al.
Published: (2014)

Safflower Yellow Injection Alleviates Myocardial Ischemia/Reperfusion Injury by Reducing Oxidative and Endoplasmic Reticulum Stress
by: Wulin Liang, et al.
Published: (2024)

Ferroptosis and myocardial ischemia-reperfusion: mechanistic insights and new therapeutic perspectives
by: Binwei Jin, et al.
Published: (2024)

Paeonol Protects Against Myocardial Ischemia/Reperfusion-Induced Injury by Mediating Apoptosis and Autophagy Crosstalk
by: Chin-Feng Tsai, et al.
Published: (2021)

Sirt1 Activation by Post-ischemic Treatment With Lumbrokinase Protects Against Myocardial Ischemia-Reperfusion Injury
by: Yi-Hsin Wang, et al.
Published: (2018)

Bauhinia championii flavone inhibits apoptosis and autophagy via the PI3K/Akt pathway in myocardial ischemia/reperfusion injury in rats
by: Jian J, et al.
Published: (2015)

Role of cytokines in myocardial ischemia and reperfusion
by: H. S. Sharma, et al.
Published: (1997)

Verapamil Alleviates Myocardial Ischemia/Reperfusion Injury by Attenuating Oxidative Stress via Activation of SIRT1
by: Mi Bao, et al.
Published: (2022)

AMPK/SIRT1 Pathway is Involved in Arctigenin-Mediated Protective Effects Against Myocardial Ischemia-Reperfusion Injury
by: Cheng-Yin Liu, et al.
Published: (2021)

Research progress on effects of traditional Chinese medicine on myocardial ischemia-reperfusion injury: A review
by: Na Xing, et al.
Published: (2022)

Hepatoma-Derived Growth Factor Secreted from Mesenchymal Stem Cells Reduces Myocardial Ischemia-Reperfusion Injury
by: Yu Zhou, et al.
Published: (2017)

N-Acetylcysteine Attenuates Diabetic Myocardial Ischemia Reperfusion Injury through Inhibiting Excessive Autophagy
by: Sheng Wang, et al.
Published: (2017)

Protective effect of picroside II on myocardial ischemia reperfusion injury in rats
by: Wu N, et al.
Published: (2014)

Amelioration of myocardial ischemia/reperfusion injury in diabetes: A narrative review of the mechanisms and clinical applications of dexmedetomidine
by: Meng Sun, et al.
Published: (2022)

Astragalin alleviates cerebral ischemia-reperfusion injury by improving anti-oxidant and anti-inflammatory activities and inhibiting apoptosis pathway in rats
by: Xiuying Chen, et al.
Published: (2020)

The combination of Tanshinone IIA and Astragaloside IV attenuates myocardial ischemia-reperfusion injury by inhibiting the STING pathway
by: Pan Zhai, et al.
Published: (2024)

Diabetes Upregulates Oxidative Stress and Downregulates Cardiac Protection to Exacerbate Myocardial Ischemia/Reperfusion Injury in Rats
by: Chen-Yen Chien, et al.
Published: (2020)

Knockdown of Sfrp4 attenuates apoptosis to protect against myocardial ischemia/reperfusion injury
by: Wenhui Zeng, et al.
Published: (2019)

Baicalin Prevents Myocardial Ischemia/Reperfusion Injury Through Inhibiting ACSL4 Mediated Ferroptosis
by: Zhenyu Fan, et al.
Published: (2021)

The Regulatory Role of Non-coding RNA in Autophagy in Myocardial Ischemia-Reperfusion Injury
by: Dan Wang, et al.
Published: (2022)

Hydroxytyrosol Protects against Myocardial Ischemia/Reperfusion Injury through a PI3K/Akt-Dependent Mechanism
by: Ying-hao Pei, et al.
Published: (2016)

LLDT-8 protects against cerebral ischemia/reperfusion injury by suppressing post-stroke inflammation
by: Yanke Chen, et al.
Published: (2016)

Inhibition of Myocardial Cell Apoptosis Is Important Mechanism for Ginsenoside in the Limitation of Myocardial Ischemia/Reperfusion Injury
by: Zhihan Chen, et al.
Published: (2022)

Retraction Note: Astragalin alleviates cerebral ischemia-reperfusion injury by improving anti-oxidant and anti-inflammatory activities and inhibiting apoptosis pathway in rats
by: Xiuying Chen, et al.
Published: (2023)

Yin and Yang of NADPH Oxidases in Myocardial Ischemia-Reperfusion
by: Shouji Matsushima, et al.
Published: (2022)

An Updated Insight Into Molecular Mechanism of Hydrogen Sulfide in Cardiomyopathy and Myocardial Ischemia/Reperfusion Injury Under Diabetes
by: Hai-Jian Sun, et al.
Published: (2021)

Bardoxolone Methyl Ameliorates Myocardial Ischemia/Reperfusion Injury by Activating the Nrf2/HO-1 Signaling Pathway
by: Anwu Huang, et al.
Published: (2023)

Anti-IL-20 Antibody Protects against Ischemia/Reperfusion-Impaired Myocardial Function through Modulation of Oxidative Injuries, Inflammation and Cardiac Remodeling
by: Kun-Ling Tsai, et al.
Published: (2021)

Single-Cell WGCNA Combined with Transcriptome Sequencing to Study the Molecular Mechanisms of Inflammation-Related Ferroptosis in Myocardial Ischemia-Reperfusion Injury
by: Zhang Z, et al.
Published: (2024)

SIRT1 is Required for Exercise-Induced Beneficial Effects on Myocardial Ischemia/Reperfusion Injury
by: Wang D, et al.
Published: (2021)

Ligustrazine Exerts Cardioprotection in Animal Models of Myocardial Ischemia/Reperfusion Injury: Preclinical Evidence and Possible Mechanisms
by: Qun Zheng, et al.
Published: (2018)

AMPK Activation Alleviates Myocardial Ischemia-Reperfusion Injury by Regulating Drp1-Mediated Mitochondrial Dynamics
by: Jingxia Du, et al.
Published: (2022)

Tongguan capsule for treating myocardial ischemia-reperfusion injury: integrating network pharmacology and mechanism study
by: Jiantao Liu, et al.
Published: (2023)

MSCs‑derived exosomes attenuate ischemia-reperfusion brain injury and inhibit microglia apoptosis might via exosomal miR-26a-5p mediated suppression of CDK6
by: Chang Cheng, et al.
Published: (2021)

Renalase Protects the Cardiomyocytes of Sprague-Dawley Rats Against Ischemia and Reperfusion Injury by Reducing Myocardial Cell Necrosis and Apoptosis
by: Xiaogang Li, et al.
Published: (2015)

Mechanisms of Electroacupuncture Pretreatment in Alleviating Myocardial Ischemia Reperfusion Injury: Interactions between the Cerebellar Fastigial Nucleus and Lateral Hypothalamic Area
by: Qing Yu, et al.
Published: (2021)

M2b macrophages stimulate lymphangiogenesis to reduce myocardial fibrosis after myocardial ischaemia/reperfusion injury
by: Cuiping Wang, et al.
Published: (2022)

Myocyte-specific overexpressing HDAC4 promotes myocardial ischemia/reperfusion injury
by: Ling Zhang, et al.
Published: (2018)