Prevention of bleomycin‐induced lung fibrosis via inhibition of the MRTF/SRF transcription pathway
Abstract Bleomycin‐induced lung fibrosis is a debilitating disease, linked to high morbidity and mortality in chemotherapy patients. The MRTF/SRF transcription pathway has been proposed as a potential therapeutic target, as it is critical for myofibroblast differentiation, a hallmark of fibrosis. In...
Saved in:
Main Authors: | Kendell M. Pawelec (Author), Megan Varnum (Author), Jack R. Harkema (Author), Bruce Auerbach (Author), Scott D. Larsen (Author), Richard R. Neubig (Author) |
---|---|
Format: | Book |
Published: |
Wiley,
2022-12-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Migration arrest of chemoresistant leukemia cells mediated by MRTF-SRF pathway
by: Maho Morimatsu, et al.
Published: (2020) -
Pulmonary Silicosis Alters MicroRNA Expression in Rat Lung and miR-411-3p Exerts Anti-fibrotic Effects by Inhibiting MRTF-A/SRF Signaling
by: Xuemin Gao, et al.
Published: (2020) -
Myocardin-Related Transcription Factor A (MRTF-A) Regulates the Balance between Adipogenesis and Osteogenesis of Human Adipose Stem Cells
by: Laura Hyväri, et al.
Published: (2020) -
Skin and lung fibrosis induced by bleomycin in mice: a systematic review
by: S. Gülle, et al.
Published: (2024) -
Interleukin-22 Inhibits Bleomycin-Induced Pulmonary Fibrosis
by: Minrui Liang, et al.
Published: (2013)