Synthesis and Evaluation of ePSMA-DM1: A New Theranostic Small-Molecule Drug Conjugate (T-SMDC) for Prostate Cancer

• Auteurs principaux: Erika Murce (Auteur), Evelien Spaan (Auteur), Savanne Beekman (Auteur), Lilian van den Brink (Auteur), Maryana Handula (Auteur), Debra Stuurman (Auteur), Corrina de Ridder (Auteur), Simone U. Dalm (Auteur), Yann Seimbille (Auteur)
• Format: Livre
• Publié: MDPI AG, 2023-07-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Small-molecule drug conjugates (SMDCs) are compounds in which a therapeutic payload is conjugated to a targeting vector, for specific delivery to the tumor site. This promising approach can be translated to the treatment of prostate cancer by selecting a targeting vector which binds to the prostate-...