Obesity Parameters as Predictor of Poor Outcomes in Hospitalized Patients with Confirmed Mild-to-Moderate COVID-19

• Main Authors: Nadya R. V. Barus (Author), Dicky Levenus Tahapary (Author), Farid Kurniawan (Author), Robert Sinto (Author), Syahidatul Wafa (Author), Wismandari Wisnu (Author), Arif Mansjoer (Author), Calysta Nadya Wijaya (Author), Immanuel Felix (Author), Tri Juli Edi Tarigan (Author), Dante Saksono Harbuwono (Author), Pradana Soewondo (Author)
• Format: Book
• Published: MDPI AG, 2024-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.
• Notes: 10.3390/idr16050071; 2036-7449
• Keywords: ARDS; waist circumference; COVID-19 severity; obesity; poor outcome; Other systems of medicine; RZ201-999
• Source: Infectious Disease Reports, Vol 16, Iss 5, Pp 894-905 (2024)

(1) Background: This study aims to assess visceral fat values, waist circumference (WC), body mass index (BMI), and body fat percentage for their ability to predict poor outcomes during COVID-19 patients' hospitalization; (2) Methods: This study was a prospective cohort of mild-moderate COVID-19 patients hospitalized at Dr. Cipto Mangunkusumo National General Hospital from December 2020 to March 2021. This study includes hospitalized patients over 18 diagnosed with COVID-19 using RT-PCR. Patients who do not have chest radiography, waist circumference, a bioimpedance analyzer (BIA) error, or are unable to stand or mobilize during the examination are excluded from this study. Cox regression was used for multivariate analysis; (3) Results: The study included two hundred sixty-one patients. The median visceral fat value was 10 (equivalent to 100 cm²), the WC was 93.4 cm, the BMI was 26.1 kg/m², and the body fat percentage was 31.5%. Based on multivariate Cox regression, WC was statistically significant as an independent factor influencing poor outcomes in COVID-19 patients (RR 1.037 [95% CI 1.011-1.064]) along with COVID-19 degree of severity (RR 3.063 [95% CI 1.537-6.104]) and comorbidities (RR 2.123 [95% CI 1.017-4.435]); (4) Conclusions: Waist circumference can influence poor outcomes in confirmed COVID-19 patients during hospitalization.