Transcriptomic profiling of diverse Aedes aegypti strains reveals increased basal-level immune activation in dengue virus-refractory populations and identifies novel virus-vector molecular interactions.

• Main Authors: Shuzhen Sim (Author), Natapong Jupatanakul (Author), José L Ramirez (Author), Seokyoung Kang (Author), Claudia M Romero-Vivas (Author), Hamish Mohammed (Author), George Dimopoulos (Author)
• פורמט: ספר
• יצא לאור: Public Library of Science (PLoS), 2013-01-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

Genetic variation among Aedes aegypti populations can greatly influence their vector competence for human pathogens such as the dengue virus (DENV). While intra-species transcriptome differences remain relatively unstudied when compared to coding sequence polymorphisms, they also affect numerous asp...