Elucidation of the inhibitory effect of (+)-hopeaphenol on polyinosinic-polycytidylic acid-induced innate immunity activation in human cerebral microvascular endothelial cells

• Main Authors: Liu Xu (Author), Zaiqiang Yu (Author), Yoshinori Uekusa (Author), Shogo Kawaguchi (Author), Haruhisa Kikuchi (Author), Kazuyuki Daitoku (Author), Masahito Minakawa (Author), Shigeru Motomura (Author), Ken-Ichi Furukawa (Author), Yoshiteru Oshima (Author), Kazuhiko Seya (Author), Tadaatsu Imaizumi (Author)
• Format: Book
• Published: Elsevier, 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Drug development for regulating the innate immune system is important for the prevention and treatment of autoinflammatory and autoimmune diseases. In this context, we investigated the effect of resveratrol derivatives on the inflammatory reactions in the brain. Resveratrol, which can be found in Vi...