Detection of PLZF- RARa Fusion in Patients with Acute Promyelocytic Leukemia
Background and Aim: Acute promyelocytic leukemia (APL) is associated with the t(15;17) ,fusing promyelocytic leukemia (PML) and retinoic acid receptor-a (RARa) genes. This disease is uniquely sensitive to treatment with all-trans retinoic acid (ATRA) and highly responsive to conventional chemotherap...
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Main Authors: | , , , , , , |
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Format: | Book |
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Tehran University of Medical Sciences,
2008-08-01T00:00:00Z.
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