Detection of PLZF- RARa Fusion in Patients with Acute Promyelocytic Leukemia

Background and Aim: Acute promyelocytic leukemia (APL) is associated with the t(15;17) ,fusing promyelocytic leukemia (PML) and retinoic acid receptor-a (RARa) genes. This disease is uniquely sensitive to treatment with all-trans retinoic acid (ATRA) and highly responsive to conventional chemotherap...

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Bibliographic Details
Main Authors: SH Rostami (Author), H Rahimi (Author), B Chardooli (Author), N Einollahi (Author), K Alimoghadam (Author), M Araghi (Author), A Ghavamzadeh (Author)
Format: Book
Published: Tehran University of Medical Sciences, 2008-08-01T00:00:00Z.
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