IgG4-related disease; a unifying entity

IgG4-related disease (IgG4-RD) is characterized by dense lymphoplasmacytic infiltration of different organs and elevated serum IgG4 level. The disease involves different organs including pancreas, kidney, aorta, lung, thyroid, salivary and lacrimal glands. IgG4-RD mimics malignancies, infectious and...

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Bibliographic Details
Main Authors: Mohammadreza Ardalan (Author), Kasra Ardalan (Author)
Format: Book
Published: Society of Diabetic Nephropathy Prevention, 2018-01-01T00:00:00Z.
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042 |a dc 
100 1 0 |a Mohammadreza Ardalan  |e author 
700 1 0 |a Kasra Ardalan  |e author 
245 0 0 |a IgG4-related disease; a unifying entity 
260 |b Society of Diabetic Nephropathy Prevention,   |c 2018-01-01T00:00:00Z. 
500 |a 2345-4202 
500 |a 10.15171/npj.2018.08 
520 |a IgG4-related disease (IgG4-RD) is characterized by dense lymphoplasmacytic infiltration of different organs and elevated serum IgG4 level. The disease involves different organs including pancreas, kidney, aorta, lung, thyroid, salivary and lacrimal glands. IgG4-RD mimics malignancies, infectious and inflammatory disorders. Many disorders previously regarded as isolated, single-organ diseases such as autoimmune pancreatitis type 1, Mikulicz disease, and Riedel thyroiditis are connected within the spectrum of IgG4-RD. Chronic interstitial nephritis (CIN) is the main type of renal involvement. Membranous nephropathy is another renal picture of IgG4-RD. Multiple, hypo-dense, cortical, round and wedge-shape lesions are the main renal ultrasound features. IgG4-RD during its inflammatory phase successfully responds to glucocorticoid therapy. Here we presented a case of IgG4-RD and then reviewed the existing literature. 
546 |a EN 
690 |a IgG4-related disease 
690 |a Chronic interstitial nephritis 
690 |a Membranous nephropathy 
690 |a Therapeutics. Pharmacology 
690 |a RM1-950 
690 |a Diseases of the genitourinary system. Urology 
690 |a RC870-923 
655 7 |a article  |2 local 
786 0 |n Journal of Nephropharmacology, Vol 7, Iss 1, Pp 36-39 (2018) 
787 0 |n http://jnephropharmacology.com/PDF/npj-7-36.pdf 
787 0 |n https://doaj.org/toc/2345-4202 
856 4 1 |u https://doaj.org/article/4504bd8dfd2140f4b13a3a8de34ff8c0  |z Connect to this object online.