Impact of Homoarginine on Myocardial Function and Remodeling in a Rat Model of Chronic Renal Failure

• Main Authors: Vitali Koch MD (Author), Christophe Weber MD (Author), Johannes H. Riffel MD (Author), Kristina Buchner BSc (Author), Sebastian J. Buss MD (Author), Selina Hein MD (Author), Derliz Mereles MD (Author), Marco Hagenmueller PhD (Author), Christian Erbel MD (Author), Winfried März MD (Author), Christian Booz MD (Author), Moritz H. Albrecht MD (Author), Thomas J. Vogl MD (Author), Norbert Frey MD (Author), Stefan E. Hardt MD (Author), Marco Ochs MD (Author)
• Format: Book
• Published: SAGE Publishing, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Purpose: Low plasma concentrations of the amino acid homoarginine (HA) have been shown to correlate with adverse cardiovascular outcome, particularly in patients with chronic kidney disease. The present study sought to investigate the effect of HA treatment on cardiac remodeling in rats undergoing a...