Miltefosine enhances infectivity of a miltefosine-resistant Leishmania infantum strain by attenuating its innate immune recognition.

<h4>Background</h4>Miltefosine (MIL) is currently the only oral drug available to treat visceral leishmaniasis but its use as first-line monotherapy has been compromised by an increasing treatment failure. Despite the scarce number of resistant clinical isolates, MIL-resistance by mutati...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Dimitri Bulté (Awdur), Lieselotte Van Bockstal (Awdur), Laura Dirkx (Awdur), Magali Van den Kerkhof (Awdur), Carl De Trez (Awdur), Jean-Pierre Timmermans (Awdur), Sarah Hendrickx (Awdur), Louis Maes (Awdur), Guy Caljon (Awdur)
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Cyhoeddwyd: Public Library of Science (PLoS), 2021-07-01T00:00:00Z.
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