New cyclopentaquinoline and 3,5-dichlorobenzoic acid hybrids with neuroprotection against oxidative stress for the treatment of Alzheimer's disease

• Main Authors: Kamila Czarnecka (Author), Małgorzata Girek (Author), Paweł Kręcisz (Author), Robert Skibiński (Author), Kamil Łątka (Author), Jakub Jończyk (Author), Marek Bajda (Author), Piotr Szymczyk (Author), Grzegorz Galita (Author), Jacek Kabziński (Author), Ireneusz Majsterek (Author), Alba Espargaró (Author), Raimon Sabate (Author), Paweł Szymański (Author)
• Format: Book
• Published: Taylor & Francis Group, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Alzheimer's disease (AD) is a progressive neurodegenerative brain disease. Thus, drugs including donepezil, rivastigmine, and galantamine are not entirely effective in the treatment of this multifactorial disease. The present study evaluates eight derivatives (3a-3h) as candidates with stronger...