Airway gene-expression classifiers for respiratory syncytial virus (RSV) disease severity in infants

• Κύριοι συγγραφείς: Lu Wang (Συγγραφέας), Chin-Yi Chu (Συγγραφέας), Matthew N. McCall (Συγγραφέας), Christopher Slaunwhite (Συγγραφέας), Jeanne Holden-Wiltse (Συγγραφέας), Anthony Corbett (Συγγραφέας), Ann R. Falsey (Συγγραφέας), David J. Topham (Συγγραφέας), Mary T. Caserta (Συγγραφέας), Thomas J. Mariani (Συγγραφέας), Edward E. Walsh (Συγγραφέας), Xing Qiu (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: BMC, 2021-02-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

Abstract Background A substantial number of infants infected with RSV develop severe symptoms requiring hospitalization. We currently lack accurate biomarkers that are associated with severe illness. Method We defined airway gene expression profiles based on RNA sequencing from nasal brush samples f...