Synthesis, and Anti-Tumor Evaluation of Some New Flurbiprofen Derivatives Against MCF-7 and WRL-68 Cell Lines

• Main Authors: Kasim S. Hmood (Author), Ammar A. Razzak Mahmood Kubba (Author), Redha I Al-bayati (Author), Abdulrahman M. Saleh (Author)
• Formato: Livro
• Publicado em: Universitas Gadjah Mada, 2021-01-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

A new series of flurbiprofen derivatives containing thiosemicarbazide moiety (3-7)  was  synthesized from flurbiprofen as parent nucleus by  esterification, hydrazide formation, and  heating with different  aryl isothiocyanate substituents, respectively. Flurbiprofen was also treated with thiosemica...