Rapamycin Attenuates High Glucose-Induced Inflammation Through Modulation of mTOR/NF-κB Pathways in Macrophages
Background: The NLRP3 inflammasome is one of the key contributors to impaired wound healing in diabetes. In this study, we assessed the role of rapamycin on high glucose-induced inflammation in THP-1-derived macrophages and investigated the underlying signaling mechanisms.Methods: THP-1-derived macr...
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Main Authors: | Jiezhi Dai (Author), Chaoyin Jiang (Author), Hua Chen (Author), Yimin Chai (Author) |
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Format: | Book |
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Frontiers Media S.A.,
2019-10-01T00:00:00Z.
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