Long non-coding RNA H19 in atherosclerosis: what role?
Abstract Atherosclerosis (AS) is widely accepted to be a multistep pathophysiological process associated with several other processes such as angiogenesis and inflammatory response. Long non-coding RNAs (lncRNAs) are non-protein coding RNAs (more than 200 nucleotides in length) and can regulate gene...
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| Main Authors: | , , , , , , |
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| Format: | Book |
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BMC,
2020-07-01T00:00:00Z.
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|---|---|---|---|
| 001 | doaj_46399e8ea9064e14b45dba4f1412c57a | ||
| 042 | |a dc | ||
| 100 | 1 | 0 | |a Xian Shi |e author |
| 700 | 1 | 0 | |a Ya-Ting Wei |e author |
| 700 | 1 | 0 | |a Heng Li |e author |
| 700 | 1 | 0 | |a Ting Jiang |e author |
| 700 | 1 | 0 | |a Xi-Long Zheng |e author |
| 700 | 1 | 0 | |a Kai Yin |e author |
| 700 | 1 | 0 | |a Guo-Jun Zhao |e author |
| 245 | 0 | 0 | |a Long non-coding RNA H19 in atherosclerosis: what role? |
| 260 | |b BMC, |c 2020-07-01T00:00:00Z. | ||
| 500 | |a 10.1186/s10020-020-00196-w | ||
| 500 | |a 1076-1551 | ||
| 500 | |a 1528-3658 | ||
| 520 | |a Abstract Atherosclerosis (AS) is widely accepted to be a multistep pathophysiological process associated with several other processes such as angiogenesis and inflammatory response. Long non-coding RNAs (lncRNAs) are non-protein coding RNAs (more than 200 nucleotides in length) and can regulate gene expression at the transcriptional and post-transcriptional levels. Recent studies suggest that lncRNA-H19 plays important roles in the regulation of angiogenesis, adipocyte differentiation, lipid metabolism, inflammatory response, cellular proliferation and apoptosis. In this review, we primarily discuss the roles of lncRNA-H19 in atherosclerosis-related pathophysiological processes and the potential mechanisms by which lncRNA-H19 regulates the development of atherosclerosis, to help provide a better understanding of the biological functions of lncRNA-H19 in atherosclerosis. | ||
| 546 | |a EN | ||
| 690 | |a LncRNA-H19 | ||
| 690 | |a Angiogenesis | ||
| 690 | |a Lipid metabolism | ||
| 690 | |a Inflammatory response | ||
| 690 | |a Atherosclerosis | ||
| 690 | |a Therapeutics. Pharmacology | ||
| 690 | |a RM1-950 | ||
| 690 | |a Biochemistry | ||
| 690 | |a QD415-436 | ||
| 655 | 7 | |a article |2 local | |
| 786 | 0 | |n Molecular Medicine, Vol 26, Iss 1, Pp 1-12 (2020) | |
| 787 | 0 | |n http://link.springer.com/article/10.1186/s10020-020-00196-w | |
| 787 | 0 | |n https://doaj.org/toc/1076-1551 | |
| 787 | 0 | |n https://doaj.org/toc/1528-3658 | |
| 856 | 4 | 1 | |u https://doaj.org/article/46399e8ea9064e14b45dba4f1412c57a |z Connect to this object online. |