Maternal and perinatal outcomes in women with and without hypertensive syndromes submitted to induction of labor with misoprostol

Objectives: To determine maternal and perinatal outcomes according to the mode of delivery in normotensive and hypertensive women bearing a live, full-term fetus, who were submitted to labor induction with misoprostol. Methods: Retrospective cohort study. The endpoints were tachysystole, uterine hyp...

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Main Authors: Rossana Mariana Carvalho de Paiva Marques (Author), Alex Sandro Rolland Souza (Author), Francisco Edson de Lucena Feitosa (Author), Aurélio Antônio Ribeiro da Costa (Author), Melania Maria Ramos Amorim (Author)
Format: Book
Published: Taylor & Francis Group, 2017-01-01T00:00:00Z.
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Summary:Objectives: To determine maternal and perinatal outcomes according to the mode of delivery in normotensive and hypertensive women bearing a live, full-term fetus, who were submitted to labor induction with misoprostol. Methods: Retrospective cohort study. The endpoints were tachysystole, uterine hyperstimulation, indications for cesarean section, severe maternal morbidity, side effects, maternal death, 1st/5th minute Apgar, neonatal death, requirement for neonatal intensive care, and birth weight (grams). The chi-square or Fisher's exact test was applied at a significance level of 5%. Risk ratios (RRs) and their 95% confidence intervals (95% CI) were calculated. Results: No significant differences were found in maternal outcome as a function of mode of delivery. First-minute Apgar score <7 was less common with vaginal deliveries in normotensive women (RR = 0.41; 95% CI: 0.18-0.90), this being the only significant difference in perinatal outcome. Conclusion: Maternal and perinatal outcomes were similar in hypertensive and normotensive women submitted to labor induction with misoprostol.
Item Description:1064-1955
1525-6065
10.1080/10641955.2016.1197935