Activation of AKT/mammalian target of rapamycin signaling in the peripheral blood of women with premature ovarian insufficiency and its correlation with FMR1 expression

• Váldodahkkit: Julia Rehnitz (Dahkki), Birgitta Messmer (Dahkki), Ulrike Bender (Dahkki), Xuan Phuoc Nguyen (Dahkki), Ariane Germeyer (Dahkki), Katrin Hinderhofer (Dahkki), Thomas Strowitzki (Dahkki), Edison Capp (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: BMC, 2022-03-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Abstract Background The protein kinase B (AKT)/mammalian target of rapamycin (mTOR) signaling pathway regulates early follicular activation and follicular pool maintenance in female germline cells. Fragile X mental retardation 1 (FMR1) regulates folliculogenesis and it is variably expressed in patie...