Cover Image

Age-related changes in DNA methylation levels at CpG sites in bull spermatozoa and in vitro fertilization-derived blastocyst-stage embryos revealed by combined bisulfite restriction analysis

Age-associated methylation changes in genomic DNA have been recently reported in spermatozoa, and these changes can contribute to decline in fertility. In a previous study, we analyzed the genome-wide DNA methylation profiles of bull spermatozoa using a human DNA methylation microarray and identifie...

Full description

Saved in:

Bibliographic Details
Main Authors:	Kumiko TAKEDA (Author), Eiji KOBAYASHI (Author), Kagetomo NISHINO (Author), Akira IMAI (Author), Hiromichi ADACHI (Author), Yoichiro HOSHINO (Author), Ken IWAO (Author), Satoshi AKAGI (Author), Masahiro KANEDA (Author), Shinya WATANABE (Author)
Format:	Book
Published:	The Society for Reproduction and Development, 2019-05-01T00:00:00Z.
Subjects:	article
Online Access:	Connect to this object online.
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Differentially methylated CpG sites related to fertility in Japanese Black bull spermatozoa: epigenetic biomarker candidates to predict sire conception rate
by: Kumiko TAKEDA, et al.
Published: (2021)

Effects of reduced glutathione supplementation in semen freezing extender on frozen-thawed bull semen and in vitro fertilization
by: Kazuko OGATA, et al.
Published: (2021)

Dynamics of microRNAs in bull spermatozoa
by: Govindaraju Aruna, et al.
Published: (2012)

Comparison of Spermatozoa Recovery Methods on Cauda Epididymal Sperm of Hanwoo Bulls
by: Sung-Sik Kang, et al.
Published: (2018)

Effect of Calcium Carbonate Encapsulation on the Activity of Orally Administered CpG Oligonucleotides
by: Neslihan Kayraklioglu, et al.
Published: (2017)

Genome-wide identification of methylated CpG sites in nongenital cutaneous warts
by: Laith N. AL-Eitan, et al.
Published: (2020)

CpG Oligodeoxynucleotides for Anticancer Monotherapy from Preclinical Stages to Clinical Trials
by: Zhongkun Zhang, et al.
Published: (2021)

In Vivo TLR9 Inhibition Attenuates CpG-Induced Myocardial Dysfunction
by: O. Boehm, et al.
Published: (2013)

Effect of DNMT3A polymorphisms on CpG island hypermethylation in gastric mucosa
by: Hikaru Takano, et al.
Published: (2020)

Characteristic of K3 (CpG-ODN) as a Transcutaneous Vaccine Formulation Adjuvant
by: Sayami Ito, et al.
Published: (2020)

Co-Encapsulated CpG Oligodeoxynucleotides and Ovalbumin in PLGA Microparticles; An in vitro and in vivo Study
by: Beatriz San Román, et al.
Published: (2014)

CpG Type A Induction of an Early Protective Environment in Experimental Multiple Sclerosis
by: James Crooks, et al.
Published: (2017)

Multiple Immunosuppressive Effects of CpG-c41 on Intracellular TLR-Mediated Inflammation
by: Wancheng Liu, et al.
Published: (2017)

Cooperative activation of human TLR9 and consequences for the clinical development of antisense and CpG oligodeoxynucleotides
by: Gunther Hartmann
Published: (2023)

Screening the genome for HCC-specific CpG methylation signatures as biomarkers for diagnosis and prognosis evaluation
by: Rui-kun Zhang, et al.
Published: (2021)

Clinical development of SpikoGen®, an Advax-CpG55.2 adjuvanted recombinant spike protein vaccine
by: Nikolai Petrovsky
Published: (2024)

Plasmacytoid Dendritic Cell Response to CpG ODN Correlates with CXCL16 Expression and Is Inhibited by ox-LDL
by: Mayda Gursel, et al.
Published: (2013)

Influence of MIF polymorphisms on CpG island hyper-methylation of CDKN2A in the patients with ulcerative colitis
by: Naoko Sakurai, et al.
Published: (2020)

Dengue-1 envelope protein domain III along with PELC and CpG oligodeoxynucleotides synergistically enhances immune responses.
by: Chen-Yi Chiang, et al.
Published: (2012)

A Novel C Type CpG Oligodeoxynucleotide Exhibits Immunostimulatory Activity In Vitro and Enhances Antitumor Effect In Vivo
by: Tete Li, et al.
Published: (2020)

Lack of increases in methylation at three CpG-rich genomic loci in non-mitotic adult tissues during aging
by: Kanel Gary C, et al.
Published: (2007)

Follistatin supplementation induces changes in CDX2 CpG methylation and improves in vitro development of bovine SCNT preimplantation embryos
by: Mohamed Ashry, et al.
Published: (2021)

PERANCANGAN PRIMER DAN DETEKSI CpG ISLAND SECARA IN SILICO PADA GEN HSP90 AYAM (Gallus gallus)
by: Nisa Sholihatul Ummah, -
Published: (2022)

Development of a quantitative ELISA for SARS-CoV-2 vaccine candidate, NDV-HXP-S, with CpG 1018® adjuvant
by: Marcus Estrada, et al.
Published: (2024)

Methyl-CpG-binding protein 2 (MECP2) mutation type is associated with bone disease severity in Rett syndrome
by: Carla Caffarelli, et al.
Published: (2020)

Nanoparticle System Based on Amino-Dextran as a Drug Delivery Vehicle: Immune-Stimulatory CpG-Oligonucleotide Loading and Delivery
by: Hien V. Nguyen, et al.
Published: (2020)

Electroacupuncture Alleviates Lung Injury in CpG1826-Challenged Mice via Modulating CD39-NLRP3 Pathway
by: Wu J, et al.
Published: (2023)

The expression of spinal methyl-CpG-binding protein 2, DNA methyltransferases and histone deacetylases is modulated in persistent pain states
by: Tochiki Keri K, et al.
Published: (2012)

CpG Oligodeoxynucleotides Inhibit RANKL-Induced Osteoclast Formation by Upregulating A20 Deubiquitinase in RAW 264.7 Cells
by: Seong-Kyu Kim, et al.
Published: (2022)

Study of photostability of nifedipine in pluronic F-127 gel using sodium bisulfite
by: Khanittha Pongpaln
Published: (2014)

The recombinant truncated envelope protein of West Nile virus adjuvanted with Alum/CpG induces potent humoral and T cell immunity in mice
by: Yongping Du, et al.
Published: (2023)

N-Acetyl-l-Leucine-Polyethyleneimine-Mediated Delivery of CpG Oligodeoxynucleotides 2006 Inhibits RAW264.7 Cell Osteoclastogenesis
by: Wang H, et al.
Published: (2020)

Improvement in blastocyst quality by neurotensin signaling via its receptors in bovine spermatozoa during in vitro fertilization
by: Kohei UMEZU, et al.
Published: (2019)

Evaluation of CpG-ODN-Adjuvanted <i>Toxoplasma gondii</i> Virus-Like Particle Vaccine upon One, Two, and Three Immunizations
by: Hae-Ji Kang, et al.
Published: (2020)

Formulation of SARS-CoV-2 Spike Protein with CpG Oligodeoxynucleotides and Squalene Nanoparticles Modulates Immunological Aspects Following Intranasal Delivery
by: Hui-Min Ho, et al.
Published: (2022)

Toll-like receptor agonists Porphyromonas gingivalis LPS and CpG differentially regulate IL-10 competency and frequencies of mouse B10 cells
by: Zhiqiang LIU, et al.

CpG ODN D35 improves the response to abbreviated low-dose pentavalent antimonial treatment in non-human primate model of cutaneous leishmaniasis.
by: Seth G Thacker, et al.
Published: (2020)

Epigenetic Scanning of <i>KEAP1</i> CpG Sites Uncovers New Molecular-Driven Patterns in Lung Adeno and Squamous Cell Carcinomas
by: Federico Pio Fabrizio, et al.
Published: (2020)

CpG Oligodeoxynucleotide Developed to Activate Primate Immune Responses Promotes Antitumoral Effects in Combination with a Neoantigen-Based mRNA Cancer Vaccine
by: Li Q, et al.
Published: (2021)

Screening significantly hypermethylated genes in fetal tissues compared with maternal blood using a methylated-CpG island recovery assay-based microarray
by: Yin Aihua, et al.
Published: (2012)