Interplay between Selenium Levels and Replicative Senescence in WI-38 Human Fibroblasts: A Proteomic Approach

• Main Authors: Ghania Hammad (Author), Yona Legrain (Author), Zahia Touat-Hamici (Author), Stéphane Duhieu (Author), David Cornu (Author), Anne-Laure Bulteau (Author), Laurent Chavatte (Author)
• Format: Book
• Published: MDPI AG, 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Selenoproteins are essential components of antioxidant defense, redox homeostasis, and cell signaling in mammals, where selenium is found in the form of a rare amino acid, selenocysteine. Selenium, which is often limited both in food intake and cell culture media, is a strong regulator of selenoprot...