Cerebrospinal fluid penetration of very high-dose meropenem: a case report
Abstract Background Standard dosing of meropenem (2 g t.i.d.) produces CSF concentrations of only 1-2 mg/L which is inferior to the clinical breakpoint for most Gram-negative bacteria. There is therefore concern that dosing must be increased in order to achieve therapeutic CSF concentrations for bac...
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BMC,
2018-12-01T00:00:00Z.
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