Cover Image

Morroniside Inhibits Inflammatory Bone Loss through the TRAF6-Mediated NF-κB/MAPK Signalling Pathway

Osteoporosis is a chronic inflammatory disease that severely affects quality of life. <i>Cornus officinalis</i> is a Chinese herbal medicine with various bioactive ingredients, among which morroniside is its signature ingredient. Although anti-bone resorption drugs are the main treatment...

Full description

Saved in:

Bibliographic Details
Main Authors:	Jirimutu Xiao (Author), Qiuge Han (Author), Ziceng Yu (Author), Mengmin Liu (Author), Jie Sun (Author), Mao Wu (Author), Heng Yin (Author), Jingyue Fu (Author), Yang Guo (Author), Lining Wang (Author), Yong Ma (Author)
Format:	Book
Published:	MDPI AG, 2023-10-01T00:00:00Z.
Subjects:	article
Online Access:	Connect to this object online.
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

18β-Glycyrrhetinic Acid Inhibits Osteoclastogenesis In Vivo and In Vitro by Blocking RANKL-Mediated RANK-TRAF6 Interactions and NF-κB and MAPK Signaling Pathways
by: Xiao Chen, et al.
Published: (2018)

Mogrol Attenuates Osteoclast Formation and Bone Resorption by Inhibiting the TRAF6/MAPK/NF-κB Signaling Pathway In vitro and Protects Against Osteoporosis in Postmenopausal Mice
by: Yongjie Chen, et al.
Published: (2022)

Pellino1 promoted inflammation in lung injury model of sepsis by TRAF6/ NF-κB signal pathway
by: Xiaqing Liu, et al.
Published: (2021)

CD137 Regulates NFATc1 Expression in Mouse VSMCs through TRAF6/NF-κB p65 Signaling Pathway
by: Jinchuan Yan, et al.
Published: (2015)

Morroniside ameliorates inflammatory skeletal muscle atrophy via inhibiting canonical and non-canonical NF-κB and regulating protein synthesis/degradation
by: Xiangjiao Yi, et al.
Published: (2022)

Etanercept Inhibits B Cell Differentiation by Regulating TNFRII/TRAF2/NF-κB Signaling Pathway in Rheumatoid Arthritis
by: Xiao-Yu Cai, et al.
Published: (2020)

Bovine Lactoferrin Suppresses Tumor Angiogenesis through NF-κB Pathway Inhibition by Binding to TRAF6
by: Nurina Febriyanti Ayuningtyas, et al.
Published: (2023)

Dencichine prevents ovariectomy-induced bone loss and inhibits osteoclastogenesis by inhibiting RANKL-associated NF-κB and MAPK signaling pathways
by: Dingwei Cang, et al.
Published: (2021)

Sesamolin Protects Mice From Ovariectomized Bone Loss by Inhibiting Osteoclastogenesis and RANKL-Mediated NF-κB and MAPK Signaling Pathways
by: Xue Yang, et al.
Published: (2021)

Plantamajoside alleviates acute sepsis-induced organ dysfunction through inhibiting the TRAF6/NF-κB axis
by: Daili Feng, et al.
Published: (2023)

Dehydrocorydaline Protects Against Sepsis-Induced Myocardial Injury Through Modulating the TRAF6/NF-κB Pathway
by: Yadong Li, et al.
Published: (2021)

Nicorandil Inhibits Osteoclast Formation Base on NF-κB and p-38 MAPK Signaling Pathways and Relieves Ovariectomy-Induced Bone Loss
by: Shenggui Xu, et al.
Published: (2021)

Sinensetin suppresses influenza a virus-triggered inflammation through inhibition of NF-κB and MAPKs signalings
by: Jiashun Li, et al.
Published: (2020)

Tussilagone Inhibits Osteoclastogenesis and Periprosthetic Osteolysis by Suppressing the NF-κB and P38 MAPK Signaling Pathways
by: Xuantao Hu, et al.
Published: (2020)

Epimedin A inhibits the PI3K/AKT/NF-κB signalling axis and osteoclast differentiation by negatively regulating TRAF6 expression
by: Jun Li, et al.
Published: (2024)

Anhuienoside C Ameliorates Collagen-Induced Arthritis through Inhibition of MAPK and NF-κB Signaling Pathways
by: Qing Liu, et al.
Published: (2017)

The mechanism of nicotinamide on reducing acute lung injury by inhibiting MAPK and NF-κB signal pathway
by: Qun Zhang, et al.
Published: (2021)

Chondro-Protective Effects of Shikimic Acid on Osteoarthritis via Restoring Impaired Autophagy and Suppressing the MAPK/NF-κB Signaling Pathway
by: Hongbo You, et al.
Published: (2021)

Fengshi Gutong Capsule Attenuates Osteoarthritis by Inhibiting MAPK, NF-κB, AP-1, and Akt Pathways
by: Yao-Xin Gao, et al.
Published: (2018)

Induction of CYP3A by morroniside in rats
by: Shan Xiong, et al.
Published: (2015)

A review of the sources and pharmacological research of morroniside
by: Pengliang Shi, et al.
Published: (2024)

Kinsenoside attenuates osteoarthritis by repolarizing macrophages through inactivating NF-κB/MAPK signaling and protecting chondrocytes
by: Feng Zhou, et al.
Published: (2019)

Recombinant Human Endostatin Suppresses Mouse Osteoclast Formation by Inhibiting the NF-κB and MAPKs Signaling Pathways
by: Non eChen, et al.
Published: (2016)

Immunoenhancement activity of Bletilla striata polysaccharide through MAPK and NF-κB signalling pathways in vivo and in vitro
by: Xiaofeng Niu, et al.
Published: (2022)

Dusuqing granules (DSQ) suppress inflammation in Klebsiella pneumonia rat via NF-κB/MAPK signaling
by: Xue Mei, et al.
Published: (2017)

Rosiglitazone Attenuates Endothelial Progenitor Cell Apoptosis Induced by TNF-α via ERK/MAPK and NF-κB Signal Pathways
by: Shengjie Xu, et al.
Published: (2011)

Asiaticoside reverses M2 phenotype macrophage polarization-evoked osteosarcoma cell malignant behaviour by TRAF6/NF-κB inhibition
by: Dang-ke Li, et al.
Published: (2022)

Valsartan attenuates LPS-induced ALI by modulating NF-κB and MAPK pathways
by: Mi Zhou, et al.
Published: (2024)

Magnoflorine Suppresses MAPK and NF-κB Signaling to Prevent Inflammatory Osteolysis Induced by Titanium Particles In Vivo and Osteoclastogenesis via RANKL In Vitro
by: Zhenyu Sun, et al.
Published: (2020)

Gamabufotalin Inhibits Osteoclastgenesis and Counteracts Estrogen-Deficient Bone Loss in Mice by Suppressing RANKL-Induced NF-κB and ERK/MAPK Pathways
by: Kaiqiang Sun, et al.
Published: (2021)

Cepharanthine Ameliorates Chondrocytic Inflammation and Osteoarthritis via Regulating the MAPK/NF-κB-Autophagy Pathway
by: Minjun Yao, et al.
Published: (2022)

Anemoside B4 ameliorates TNBS-induced colitis through S100A9/MAPK/NF-κB signaling pathway
by: Yong Zhang, et al.
Published: (2021)

Cordycepin Protects against Hepatic Ischemia/Reperfusion Injury via Inhibiting MAPK/NF-κB Pathway
by: Jiameng Ding, et al.
Published: (2022)

<i>Artemisia gmelinii</i> Attenuates Lung Inflammation by Suppressing the NF-κB/MAPK Pathway
by: Seung Yong Kim, et al.
Published: (2022)

Dietary Curcumin Attenuates Hepatic Cellular Senescence by Suppressing the MAPK/NF-κB Signaling Pathway in Aged Mice
by: Da-Yeon Lee, et al.
Published: (2023)

Liraglutide attenuates gefitinib-induced cardiotoxicity and promotes cardioprotection through the regulation of MAPK/NF-κB signaling pathways
by: Abdullah F. AlAsmari, et al.
Published: (2020)

Astragaloside IV Relieves Atherosclerosis and Hepatic Steatosis via MAPK/NF-κB Signaling Pathway in LDLR−/− Mice
by: Yifan Zhang, et al.
Published: (2022)

α-Mangostin inhibits LPS-induced bone resorption by restricting osteoclastogenesis via NF-κB and MAPK signaling
by: Wenkan Zhang, et al.
Published: (2022)

Amphiregulin Induces iNOS and COX-2 Expression through NF-κB and MAPK Signaling in Hepatic Inflammation
by: Yu Jung Heo, et al.
Published: (2023)

Protective Effect of Fluorofenidone Against Acute Lung Injury Through Suppressing the MAPK/NF-κB Pathway
by: Xin Lv, et al.
Published: (2021)