A Case of Basal Cell Carcinoma with Outer Hair Follicle Sheath Differentiation

A 70-year-old Japanese man presented at our hospital with an asymptomatic, blackish, irregularly shaped plaque with a gray nodule in the periphery on his left lower leg. The lesion had been present for 10 years and had recently enlarged, associated with bleeding. Histopathologically, the tumor consi...

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Main Authors: Masazumi Onishi (Author), Kazuhiro Takahashi (Author), Fumihiko Maeda (Author), Toshihide Akasaka (Author)
Format: Book
Published: Karger Publishers, 2015-12-01T00:00:00Z.
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042 |a dc 
100 1 0 |a Masazumi Onishi  |e author 
700 1 0 |a Kazuhiro Takahashi  |e author 
700 1 0 |a Fumihiko Maeda  |e author 
700 1 0 |a Toshihide Akasaka  |e author 
245 0 0 |a A Case of Basal Cell Carcinoma with Outer Hair Follicle Sheath Differentiation 
260 |b Karger Publishers,   |c 2015-12-01T00:00:00Z. 
500 |a 1662-6567 
500 |a 10.1159/000442704 
520 |a A 70-year-old Japanese man presented at our hospital with an asymptomatic, blackish, irregularly shaped plaque with a gray nodule in the periphery on his left lower leg. The lesion had been present for 10 years and had recently enlarged, associated with bleeding. Histopathologically, the tumor consisted of three distinct parts: The first part showed massive aggregation of basophilic basaloid cells with peripheral palisading and abundant melanin granules, and was diagnosed as solid-type basal cell carcinoma. The second part showed aggregation of clear cells with squamous eddies, and was diagnosed as proliferating trichilemmal tumor. The third part showed reticular aggregation of basaloid cells with infundibular cysts in the papillary dermis, and was diagnosed as infundibulocystic basal cell carcinoma. We diagnosed this tumor as basal cell carcinoma with various forms of hair follicle differentiation, including differentiation into the outer root sheath. 
546 |a EN 
690 |a Follicular differentiation 
690 |a Solid-type basal cell carcinoma 
690 |a Proliferating trichilemmal tumor 
690 |a Infundibulocystic basal cell carcinoma 
690 |a Dermatology 
690 |a RL1-803 
655 7 |a article  |2 local 
786 0 |n Case Reports in Dermatology, Vol 7, Iss 3, Pp 352-357 (2015) 
787 0 |n http://www.karger.com/Article/FullText/442704 
787 0 |n https://doaj.org/toc/1662-6567 
856 4 1 |u https://doaj.org/article/482510f8a1bb4c5693bccdba71cb3d2e  |z Connect to this object online.