Leydig tumor in normal sized ovaries causing clitoromegaly: A case report

We describe an unusual presentation of a rare Leydig tumor presenting in bilateral ovaries that are otherwise normal in size for postmenopausal women. A 66-year-old woman presented with postmenopausal bleeding and during her work-up acutely developed clitoromegaly. Her diagnostic work-up revealed a...

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Bibliographic Details
Main Authors: Thomas F Chavez (Author), Minita Singh (Author), Vaidehi Avadhani (Author), Regina Leonis (Author)
Format: Book
Published: Elsevier, 2024-04-01T00:00:00Z.
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Summary:We describe an unusual presentation of a rare Leydig tumor presenting in bilateral ovaries that are otherwise normal in size for postmenopausal women. A 66-year-old woman presented with postmenopausal bleeding and during her work-up acutely developed clitoromegaly. Her diagnostic work-up revealed a 1.8 cm left ovarian complex cyst and extremely elevated testosterone levels. Management included hysterectomy and bilateral salpingo-oophorectomy. Final pathology revealed Leydig tumors in the bilateral ovaries. This case discusses a rare presentation of a rare tumor and highlights the importance of a thorough examination of the female genitalia and investigation for root cause.
Item Description:2352-5789
10.1016/j.gore.2024.101345