Sustainable recovery of MBNL activity in autoregulatory feedback loop in myotonic dystrophy
Muscleblind-like proteins (MBNLs) are RNA-binding proteins essential for the developmental regulation of various processes including alternative splicing. Their activity is misregulated in myotonic dystrophy type 1 (DM1), an incurable genetic, neuro-muscular disorder caused by uncontrolled expansion...
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| Format: | Book |
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Elsevier,
2022-12-01T00:00:00Z.
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