In Vitro Skin Permeation of Idebenone from Lipid Nanoparticles Containing Chemical Penetration Enhancers

• Main Authors: Lucia Montenegro (Author), Ludovica Maria Santagati (Author), Maria Grazia Sarpietro (Author), Francesco Castelli (Author), Annamaria Panico (Author), Edy Angela Siciliano (Author), Francesco Lai (Author), Donatella Valenti (Author), Chiara Sinico (Author)
• Format: Book
• Published: MDPI AG, 2021-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Lipid nanoparticles (LNPs) have been proposed as carriers for drug skin delivery and targeting. As LNPs effectiveness could be increased by the addition of chemical penetration enhancers (PE), in this work, the feasibility of incorporating PE into LNPs to improve idebenone (IDE) targeting to the ski...