The effect of combined Moringa oleifera and demineralized freeze-dried bovine bone xenograft on the amount of osteoblast and osteoclast in the healing of tooth extraction socket of Cavia cobaya

Background: Alveolar bone has an important role in providing support to teeth and dentures. Loss of support caused by alveolar resorption will cause functional and aesthetic problems. Preservation socket using bone graft is one way to maintain the dimensions of the alveolar bone. Moringa oleifera le...

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Main Authors: Rostiny Rostiny (Author), Eha Djulaeha (Author), Nike Hendrijantini (Author), Agus Pudijanto (Author)
Format: Book
Published: Universitas Airlangga, 2016-12-01T00:00:00Z.
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001 doaj_48ee81046ae942da9c0a81d29a928c3d
042 |a dc 
100 1 0 |a Rostiny Rostiny  |e author 
700 1 0 |a Eha Djulaeha  |e author 
700 1 0 |a Nike Hendrijantini  |e author 
700 1 0 |a Agus Pudijanto  |e author 
245 0 0 |a The effect of combined Moringa oleifera and demineralized freeze-dried bovine bone xenograft on the amount of osteoblast and osteoclast in the healing of tooth extraction socket of Cavia cobaya 
260 |b Universitas Airlangga,   |c 2016-12-01T00:00:00Z. 
500 |a 1978-3728 
500 |a 2442-9740 
500 |a 10.20473/j.djmkg.v49.i1.p37-42 
520 |a Background: Alveolar bone has an important role in providing support to teeth and dentures. Loss of support caused by alveolar resorption will cause functional and aesthetic problems. Preservation socket using bone graft is one way to maintain the dimensions of the alveolar bone. Moringa oleifera leaf can increase the activity of bone graft in the formation of new bone. Purpose: This study was aimed to evaluate the effect of combined Moringa oleivera leaf extract and demineralized freeze-dried bovine bone xenograft (DFDBBX) towards the formation of osteoblasts and osteoclasts in the tooth extraction sockets of cavia cobaya. Method: This study used 28 cavia cobayas divided into four groups. The combination of Moringa oleifera leaf extract and DFDBBX was inducted into the sockets of lower incisor tooth with certain dose in each group, ointment 1 containing PEG (a mixture of PEG 400 and PEG 4000) for control group, ointment 2 containing Moringa oleifera leaf extract and DFDBBX and PEG (at active subtance consentration of 0.5%) for group 1, ointment 3 containing Moringa oleifera leaf extract and DFDBBX and PEG (at active substance concentration of 1%) for group 2, and Ointment 4 containing Moringa oleifera leaf extract and DFDBBX and PEG (at active substance consentration of 2%) for group 3. paraffin block preparations were made for histopathology examination using hematoxylin eosin staining. Result: The results showed that there were significant differences of the number of osteoblasts and osteoclasts in each treatment group (p <0.05). Conclusion: It can be concluded that the combination of Moringa oleifera leaf extract and DFDBBX at 2% cocentration can increase the number of osteoblasts and decrease osteoclasts in the healing of tooth extraction sockets of cavia cobaya. 
546 |a EN 
690 |a demineralized freeze-dried bovine bone xenograft 
690 |a Moringa oleifera leaf 
690 |a osteoblast 
690 |a osteoclast 
690 |a Dentistry 
690 |a RK1-715 
655 7 |a article  |2 local 
786 0 |n Dental Journal, Vol 49, Iss 1, Pp 37-42 (2016) 
787 0 |n http://e-journal.unair.ac.id/index.php/MKG/article/view/1580 
787 0 |n https://doaj.org/toc/1978-3728 
787 0 |n https://doaj.org/toc/2442-9740 
856 4 1 |u https://doaj.org/article/48ee81046ae942da9c0a81d29a928c3d  |z Connect to this object online.