Molecular pharmacology of the onco-TRP channel TRPV6

• Huvudupphovsmän: Arthur Neuberger (Författare, medförfattare), Alexander I. Sobolevsky (Författare, medförfattare)
• Materialtyp: Bok
• Publicerad: Taylor & Francis Group, 2023-12-01T00:00:00Z.
• Ämnen: article
• Länkar: Connect to this object online.

ABSTRACTTRPV6, a representative of the vanilloid subfamily of TRP channels, serves as the principal calcium uptake channel in the gut. Dysregulation of TRPV6 results in disturbed calcium homeostasis leading to a variety of human diseases, including many forms of cancer. Inhibitors of this oncochanne...