Synthesis and anticonvulsant activity of 6-methyl-2-((2-oxo-2-arylethyl)thio)pyrimidin-4(3 H)-one derivatives and products of their cyclization

• Váldodahkkit: Hanna I. Severina (Dahkki), Olga O. Skupa (Dahkki), Natalya I. Voloshchuk (Dahkki), Marharyta M. Suleiman (Dahkki), Victoriya A. Georgiyants (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Pensoft Publishers, 2019-12-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

The alkylation of 6-methyl-2-thioxo-2,3-dihydro-1H-pyrimidine-4-one phenacyl bromides under different conditions was investigated. It was found that during the reaction in the medium of DMF/K2CO3 a mixture of 2-(2-aryl-2-oxoethyl)thio-6-methyl-pyrimidine-4(3H)-one and 3-hydroxy-3-aryl-7-methyl-2,3-d...