Direct Powder Extrusion 3D Printing of Praziquantel to Overcome Neglected Disease Formulation Challenges in Paediatric Populations

• Автори: Janine Boniatti (Автор), Patricija Januskaite (Автор), Laís B. da Fonseca (Автор), Alessandra L. Viçosa (Автор), Fábio C. Amendoeira (Автор), Catherine Tuleu (Автор), Abdul W. Basit (Автор), Alvaro Goyanes (Автор), Maria-Inês Ré (Автор)
• Формат: Книга
• Опубліковано: MDPI AG, 2021-07-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

For the last 40 years, praziquantel has been the standard treatment for schistosomiasis, a neglected parasitic disease affecting more than 250 million people worldwide. However, there is no suitable paediatric formulation on the market, leading to off-label use and the splitting of commercial tablet...