Sequential delivery of dual drugs with nanostructured lipid carriers for improving synergistic tumor treatment effect

• Main Authors: Man Xu (Author), Guangmeng Li (Author), Haoxiang Zhang (Author), Xiaoming Chen (Author), Yi Li (Author), Qianming Yao (Author), Maobin Xie (Author)
• Format: Book
• Published: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

To improve synergistic anticancer efficacy and minimize the adverse effects of chemotherapeutic drugs, temozolomide (TMZ) and curcumin (CUR) co-loaded nanostructured lipid carriers (NLCs) were prepared by microemulsion in this study. And the physicochemical properties, drug release behavior, intrace...