Stereospecific antiseizure activity in mouse and rat epilepsy models by a pyridinium inhibitor of TNFα/NFκB signaling
Epilepsy affects over 50 million people worldwide and increases the risk of death. An intrinsic state of central inflammation, mainly driven by TNFα/NFκB signaling, may contribute to the refractory nature of some epilepsies. We have therefore hypothesized that inhibitors of this signaling pathway mi...
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Main Authors: | Bette S. Pollard (Author), Zhiwei Wen (Author), Kenneth A. Jacobson (Author), John R. Pollard (Author) |
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Format: | Book |
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Elsevier,
2022-12-01T00:00:00Z.
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