D-Cysteine Ethyl Ester Reverses the Deleterious Effects of Morphine on Breathing and Arterial Blood-Gas Chemistry in Freely-Moving Rats

• Main Authors: Paulina M. Getsy (Author), Santhosh M. Baby (Author), Walter J. May (Author), Alex P. Young (Author), Benjamin Gaston (Author), Matthew R. Hodges (Author), Hubert V. Forster (Author), James N. Bates (Author), Christopher G. Wilson (Author), Tristan H. J. Lewis (Author), Yee-Hee Hsieh (Author), Stephen J. Lewis (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cell-penetrant thiol esters including the disulfides, D-cystine diethyl ester and D-cystine dimethyl ester, and the monosulfide, L-glutathione ethyl ester, prevent and/or reverse the deleterious effects of opioids, such as morphine and fentanyl, on breathing and gas exchange within the lungs of unan...