Biliary excretion and enterohepatic circulation of thienorphine and its glucuronide conjugate in rats
Thienorphine (TNP) is a new partial opioid agonist currently developed as a promising drug candidate with the intended clinical indication for the treatment of opioid dependence. The pharmacokinetic profile and biliary excretion of TNP and its glucuronide conjugate (TNP-Glu) were investigated after...
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Main Authors: | Jingting Deng (Author), Xiaomei Zhuang (Author), Guolin Shen (Author), Hua Li (Author), Zehui Gong (Author) |
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Format: | Book |
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Elsevier,
2012-04-01T00:00:00Z.
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