Evaluation of a high-throughput peptide reactivity format assay for assessment of the skin sensitization potential of chemicals

• Main Authors: Chin Lin eWong (Author), Ai Leen eLam (Author), Maree Therese Smith (Author), Sussan eGhassabian (Author)
• Format: Book
• Published: Frontiers Media S.A., 2016-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The direct peptide reactivity assay (DPRA) is a validated method for in vitro assessment of the skin sensitization potential of chemicals. In the present work, we describe a peptide reactivity assay using 96-well plate format and systematically identified the optimal assay conditions for accurate an...